Kalman tracking of linear predictor and harmonic noise models for noisy speech enhancement

This paper presents a speech enhancement method based on the tracking and denoising of the formants of a linear prediction (LP) model of the spectral envelope of speech and the parameters of a harmonic noise model (HNM) of its excitation. The main advantages of tracking and denoising the prominent energy contours of speech are the efficient use of the spectral and temporal structures of successive speech frames and a mitigation of processing artefact known as the ‘musical noise’ or ‘musical tones’.The formant-tracking linear prediction (FTLP) model estimation consists of three stages: (a) speech pre-cleaning based on a spectral amplitude estimation, (b) formant-tracking across successive speech frames using the Viterbi method, and (c) Kalman filtering of the formant trajectories across successive speech frames.The HNM parameters for the excitation signal comprise; voiced/unvoiced decision, the fundamental frequency, the harmonics’ amplitudes and the variance of the noise component of excitation. A frequency-domain pitch extraction method is proposed that searches for the peak signal to noise ratios (SNRs) at the harmonics. For each speech frame several pitch candidates are calculated. An estimate of the pitch trajectory across successive frames is obtained using a Viterbi decoder. The trajectories of the noisy excitation harmonics across successive speech frames are modeled and denoised using Kalman filters.The proposed method is used to deconstruct noisy speech, de-noise its model parameters and then reconstitute speech from its cleaned parts. Experimental evaluations show the performance gains of the formant tracking, pitch extraction and noise reduction stages

The Effects of Avian Influenza News on Consumer Purchasing Behavior: A Case Study of Italian Consumers' Retail Purchases

To better understand how information about potential health hazards influences food demand, this case study examines consumers’ responses to newspaper articles on avian influenza, informally referred to as bird flu. The focus here is on the response to bird flu information in Italy as news about highly pathogenic H5N1 avian influenza (HPAI H5N1) unfolded in the period October 2004 through October 2006, beginning after reports of the first outbreaks in Southeast Asia and extending beyond the point at which outbreaks were reported in Western Europe. Estimated poultry demand, as influenced by the volume of newspaper reports on bird flu, reveals the magnitude and duration of newspaper articles’ impacts on consumers’ food choices. Larger numbers of bird flu news reports led to larger reductions in poultry purchases. Most impacts were of limited duration, and all began to diminish within 5 weeks.Avian influenza, bird flu, consumer behavior, food safety, poultry sales and consumption, risk perception and response, Agricultural and Food Policy, Health Economics and Policy, Institutional and Behavioral Economics, International Relations/Trade,

Wavelet speech enhancement based on time-scale adaptation

Abstract : We propose a new speech enhancement method based on time and scale adaptation of wavelet thresholds. The time dependency is introduced by approximating the Teager Energy of the wavelet coefficients, while the scale dependency is introduced by extending the principle of level dependent threshold to Wavelet Packet Thresholding. This technique does not require an explicit estimation of the noise level or of the apriori knowledge of the SNR, as is usually needed in most of the popular enhancement methods. Performance of the proposed method is evaluated on speech recorded in real conditions (plane, sawmill, tank, subway, babble, car, exhibition hall, restaurant, street, airport, and train station) and artificially added noise. MELscale decomposition based on wavelet packets is also compared to the common wavelet packet scale. Comparison in terms of Signal-to-Noise Ratio (SNR) is reported for time adaptation and time-scale adaptation thresholding of the wavelet coefficients thresholding. Visual inspection of spectrograms and listening experiments are also used to support the results. Hidden Markov Models Speech recognition experiments are conducted on the AURORA–2 database and show that the proposed method improves the speech recognition rates for low SNRs

The impact of electron anisotropy on the polarization of the X-ray emission from black hole accretion disks and implications for the black hole X-ray binary 4U 1630-47

The Imaging X-ray Polarimetry Explorer (IXPE) observations of the X-ray binary 4U 1630-47 in the high soft state revealed linear polarization degrees (PDs) rising from 6% at 2 keV to 10% at 8 keV. Explaining the results in the framework of the standard optically thick, geometrically thin accretion disk scenario requires careful fine-tuning of the relevant model parameters. We argue here that the emission of polarized Bremsstrahlung by anisotropic electrons in the accretion disk atmosphere can account for the overall high PDs and the increase of the PDs with energy. We discuss plasma and accretion effects that can generate electron anisotropies at a level required by the 4U 1630-47 results. We conclude by emphasizing that X-ray polarimetry affords us the opportunity to obtain information about the magnetization of the accretion disk atmosphere.Comment: 8 pages and 6 figures, submitted to the Astrophysical Journal Letter

Pediatric sleep-related breathing disorders: advances in imaging and computational modeling

We understand now that sleep of sufficient length and quality is required for good health. This is particularly true for infants and children, who have the added physiologic task of growth and development, as compared to their adult counterparts. Sleep-related breathing disorders (SRBDs) are common in childhood and if unrecognized and not treated can result in significant morbidity. For example, children with obstructive sleep apnea (OSA) can exhibit behavioral, mood, and learning difficulties. If left untreated, alterations in the function of the autonomic nervous system and a chronic inflammatory state result, contributing to the risk of heart disease, stroke, glucose intolerance, and hypertension in adulthood

Reconstruction-based speech enhancement from robust acoustic features

This paper proposes a method of speech enhancement where a clean speech signal is reconstructed from a sinusoidal model of speech production and a set of acoustic speech features. The acoustic features are estimated from noisy speech and comprise, for each frame, a voicing classification (voiced, unvoiced or non-speech), fundamental frequency (for voiced frames) and spectral envelope. Rather than using different algorithms to estimate each parameter, a single statistical model is developed. This comprises a set of acoustic models and has similarity to the acoustic modelling used in speech recognition. This allows noise and speaker adaptation to be applied to acoustic feature estimation to improve robustness. Objective and subjective tests compare reconstruction-based enhancement with other methods of enhancement and show the proposed method to be highly effective at removing noise

Hazards Analysis and Failure Modes and Effects Criticality Analysis (FMECA) of Four Concept Vehicle Propulsion Systems

The primary objective of this research effort is to identify failure modes and hazards associated with the concept vehicles and to perform functional hazard analyses (FHA) and failure modes and effects criticality analyses (FMECA) for each. Boeing also created a Fault Tree Analysis (FTA) for each of the concept vehicles, as the FTA contains the connectivity between systems and is an accepted, top-down method to analyze the safety of an air-vehicle. Conceptual design of notional powertrain configuration for each of four (4) NASA RVLT (Revolutionary Vertical Lift Technology) Concept Vehicles were developed in as much detail as was necessary to support the reliability and safety analysis for this project. Functional block diagrams from each of the conceptual powertrain configurations were created and used to order the FHA, FMECA, and FTA. Hazards were identified and the severity of each were categorized in the FHA for use in a follow-up FMECA. The FTA took inputs from the FMECA and the functional block diagrams to develop the connectivity and develop a quantitative architecture that could be used to perform sensitivity studies, as related to vehicle safety.Guidelines for reliability targets for both the air vehicle and the operation in the UAM (Urban Air Mobility) mission are discussed. An industry literature search was performed in order to assess gaps in existing government regulations and industry specifications. The industry literature search led to air-vehicle and operational reliability discussions, as related to Distributed Electric/Hybrid-Electric Propulsion (DE/HEP) system operating in the UAM role. A discussion of results and recommendations for future work is also provided

Results of minimally toxic nonmyeloablative transplantation in patients with sickle cell anemia and β-thalassemia

AbstractWe describe previously transfused patients with sickle cell disease (n = 6) and thalassemia (n = 1) who received nonmyeloablative hematopoietic stem cell transplantation (HCT) to induce stable (full or partial) donor engraftment. Patients were 3 to 20 years (median, 9 years) old. All 7 received pretransplantation fludarabine and 200 cGy of total body irradiation; 2 patients also received horse antithymocyte globulin. Patients received bone marrow (n = 6) or peripheral blood stem cells (n = 1) from HLA-identical siblings, followed by a combination of mycophenolate mofetil and cyclosporine or tacrolimus for postgrafting immunosuppression. After nonmyeloablative HCT, absolute neutrophil counts were <0.5 × 109/L and <0.2 × 109/L for a median of 5 days (range, 0–13 days) and 0 days (range 0–13 days), respectively. A median of 0 (range, 0–9) platelet transfusions were administered. No grade IV nonhematologic toxicities were observed. One patient experienced grade II acute graft-versus-host disease. Two months after transplantation, 6 of 7 patients had evidence of donor chimerism (range, 25%–85%). Independent of red blood cell transfusions, these 6 patients initially had increased total hemoglobin and hemoglobin A concentrations and a reduction of reticulocytosis and transfusion requirements. There were no complications attributable to sickle cell disease during the interval of transient mixed chimerism. However, after posttransplantation immunosuppression was tapered, there was loss of the donor graft, and all patients experienced autologous hematopoietic recovery and disease recurrence. One patient did not engraft. The duration of transient mixed chimerism ranged from 97 to 441 days after transplantation in patients 4 and 6, respectively, and persisted until immunosuppressive drugs were discontinued after transplantation. In summary, the nonmyeloablative HCT regimens described here produced minimal toxicity and resulted in transient donor engraftment in 6 of 7 patients with hemoglobinopathies. Although complications from the underlying hemoglobinopathies did not occur during the period of mixed chimerism, these results suggest that stable (full or partial) donor engraftment after nonmyeloablative HCT is more difficult to achieve among immunocompetent pediatric patients with hemoglobinopathies than among adults with hematologic malignancies, perhaps in part because recipients may have been sensitized to minor histocompatibility antigens of their donor by preceding blood transfusions